Our Faculty

Nigel Yarlett

Distinguished Professor
Director

Dyson College of Arts and Sciences

Chemistry and Physical Sciences

Location
  • @New York City
    41 Park Row 606
Office Hours

Spring 2015

Office Hours

Spring 2015

Office Hours

Spring 2015

"In the fields of observation chance favors the prepared mind." Louis Pasteur.

Biography


Awarded a Fellow of the Royal Society of Chemistry (2012); Fellow of the Society of Fellows of Pace University (1996); Hutner Prize in Protozoology (1995); Kenan Teaching Award (2003); Lady Glanely Scholarship (1978). Over 100 publications in the area of protozoan biochemistry. Demonstrated the presence of hydrogenosomes in Rumen protozoa and Rumen fungi. The role of oxygen in the resistance of Trichomonas vaginalis to metronidazole. The unique polyamine bichemistry of Trichomonas vaginalis and Cryptosporidium parvum. The ability of oxoboroles to cure mouse model trypanosomiasis. Novel culture method for Cryptosporidium parvum. Funded by the National Institutes of Health; Drugs for Neglected Diseases initiative, and the Bill and Melinda Gates Foundation.

Education


University of Wales Fellowship, Cardiff University, Cardiff, Wales, UK, 1986
Biochemical Parsitology

Visiting Fellow, Cambridge University, United Kingdom, 1986
Anaerobic Biochemistry

Post-Doctoral, Rockefeller University, New York, 1984
Biochemical Cytology

PhD, Cardiff University/Hannah Research Institute, Cardiff, Wales/ Ayr, Scotland, 1982
Biochemistry

BS, Cardiff University, Cardiff, Wales, UK, 1979
Microbiology

Awards and Honors


Royal Society of Chemistry, March 01, 2012 - Fellow of the Royal Society of Chemistry
Pace University, May 2003 - Kenan Award for Teaching Excellence
Pace University, July 1996 - Fellow of the Society of Fellows of Pace University
International Society for Protistology, June 14, 1996 - Hutner Prize
University of Wales, September 14, 1978 - Lady Glanely Scholarship


LICENSURES & CERTIFICATES


  • NYSDOH, September 01 Radiation Safety Officer
    University RSO responsible for ensuring compliance with City, State and Federal guidelines. First responder in NYC for radiation emergency.

Publications


Continuous culture of Cryptosporidium parvum using hollow fiber technology
Morada, M., Lee, S., Gunther-Cummins, L., Weiss, L., Widmer, G., Tzipori, S. & Yarlett, N. (1995). International Journal of Parasitology. Vol in press

RESEARCH INTEREST


My Research is focused on the biochemistry and molecular biology of parasitic protozoa, particularly Cryptosporidia sp., and Trypanosomes. My research has resulted in the development of a new class of compound, the oxaboroles, to treat human African trypanosomiasis (HAT) that is currently in phase II clinical trials in Africa. I am also developing a novel culture system to facilitate the screening of novel compounds for the treatment of cryptosporidosis.

Intellectual Property


Patent: Treatment of diseases caused by parasitic protozoa and fungal diseases by administration of 5'-deoxy-5'-(substituted) ethylthioribose compounds[Non-Provisional]
United States

Patent: Adenosine compounds for the treatment of diseases caused by parasitic protozoa[Non-Provisional]
United States

Patent: 5'Deoxy-5'-(substituted) alkylthioribose compounds and their pharmaceutical compositions.[Non-Provisional]
United States

PROFESSIONAL MEMBERSHIPS


Royal Society of Chemistry[Fellow]

New York Academy of Science

American Society for Biochemistry and Molecular Biology[Member]

International Society for Protistologists[Member at Large, Editorial Board, Treasurer]

Society for General Microbiology[Editor]

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